1. Anti-infection
  2. Antibiotic Bacterial
  3. Clovibactin

Clovibactin 是一种抗生素,对耐药细菌病原体具有抑制活性,且未检测到耐药性。Clovibactin 通过靶向肽聚糖前体的焦磷酸盐抑制细胞壁合成。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

Clovibactin Chemical Structure

Clovibactin Chemical Structure

CAS No. : 2247194-77-8

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Clovibactin 的其他形式现货产品:

Other Forms of Clovibactin:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Clovibactin is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors[1].

体外研究
(In Vitro)

Clovibactin TFA 对葡萄球菌菌株具有抑制活性,MIC 为 0.125-2 μg/mL[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Clovibactin TFA (20 mg/kg,静脉注射,单剂量) 在 CD-1 小鼠模型中的药代动力学特征为 Cmax 为 219.3 μg/mL,AUCto last 为 31.9 μg·h/mL,t1/2 为 2 h,CL 为 9.4 mL/kg/min 以及 Vdss 为 189.8 mL/kg[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

903.08

Formula

C43H70N10O11

CAS 号
Sequence

Phe-{d-Leu}-{d-Lys}-Ser-{Hyn}-Ala-Leu-Leu (Cyclic ester: Hyn5-Leu8)

Sequence Shortening

F-{d-Leu}-{d-Lys}-S-{Hyn}-ALL (Cyclic ester: Hyn5-Leu8)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Clovibactin
目录号:
HY-P10027
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